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Additionally, hormonal imbalances that affect the production of sperm can lead to male infertility

doi: 10.1172/JCI116186 5 MiyawakiKYamadaYBanNIharaYTsukiyamaKZhouHet al

Colchicine has interactions with certain other medications, most notably clarithromycin (Biaxin)

It is generally agreed that we have no evidence that febuxostat is a negative for the heart, just the question of the CARES trial as to whether it is not as protective as allopurinol